Batch Details: KPV10-A1
KPV is a research-grade tripeptide corresponding to the C-terminal region of α-melanocyte-stimulating hormone (α-MSH). It exhibits strong anti-inflammatory activity while avoiding melanotropic effects associated with the full-length hormone. KPV has been widely utilized in studies exploring cytokine suppression, tissue protection, epithelial regeneration, and modulation of innate immune responses.
Research Significance
Downregulation of pro-inflammatory cytokines and pathways (e.g., NF-κB–associated mechanisms)
Enhancement of epithelial barrier stability and tissue-repair processes
Non-melanogenic α-MSH derivative, allowing isolation of anti-inflammatory pathways
Demonstrated protective effects in models of inflammatory and oxidative stress
Potential Research Applications
Inflammatory bowel, skin, and mucosal biology research
Epithelial barrier function and wound-healing studies
Immunomodulation and cytokine-signaling investigations
Comparative studies with other α-MSH fragments and melanocortin derivatives
Specifications
Form: Lyophilized peptide powder
Content: KPV 10 mg per vial
Identity: Tripeptide Lys-Pro-Val (KPV), α-MSH C-terminal fragment
Storage: Store at −20 °C; once reconstituted, use promptly under sterile lab conditions
