Batch Details: SERM5-A2
Sermorelin is a research-grade analogue of endogenous GHRH comprising the first 29 amino acids with a C-terminal amide for enhanced stability. Its rapid pharmacokinetic profile preserves physiological pulsatility of GH secretion, making it a versatile tool for time-resolved endocrine experiments and comparative studies with other secretagogues.
Research Significance
Direct activation of pituitary GHRH receptors to stimulate GH and modulate IGF-1
Short duration of action ideal for modeling physiological GH pulsatility and feedback (somatostatin/GH autoregulation)
Useful probe for hypothalamic–pituitary–somatotropic axis sensitivity and desensitization
Compatible with combination studies alongside ghrelin receptor agonists to assess synergistic secretagogue effects
Potential Research Applications
Endocrine pathway mapping of GH/IGF-1 signaling and target-tissue transcriptional responses
Metabolic investigations of lipid, glucose, and protein turnover downstream of GH
Body composition and tissue remodeling models (lean mass/adiposity endpoints)
Chronobiology and dosing-schedule studies requiring precise temporal control of GH pulses
Specifications
Form: Lyophilized peptide powder
Content: Sermorelin
Identity: GHRH(1–29) amide (GRF(1–29)NH₂)
Storage: Store at −20 °C; once reconstituted, use promptly under sterile lab conditions
