Batch Details: CND5-A1
CJC-1295 no DAC is a research-grade peptide that retains high affinity for the GHRH receptor while omitting the Drug Affinity Complex (DAC) that extends circulation time. This design provides enhanced resistance to degradation versus native GHRH(1–29) yet preserves a rapid pharmacokinetic profile, supporting experiments that require discrete, pulse-like GH stimulation and precise temporal control of endocrine readouts.
Research Significance
Robust activation of pituitary GH secretion and modulation of IGF-1
Short-acting kinetics for modeling physiological GH pulsatility
Tool for dissecting hypothalamic–pituitary–somatotropic axis responsiveness
Synergy studies with ghrelin receptor agonists to probe combined secretagogue effects
Potential Research Applications
Endocrine pathway mapping of GH/IGF-1 signaling
Metabolic studies involving glucose, lipid, and protein turnover downstream of GH
Body composition and tissue remodeling models (lean mass, adiposity)
Chronobiology experiments on timing-dependent hormone release
Specifications
Form: Lyophilized peptide powder
Content: CJC-1295 w/o DAC 5 mg per vial
Identity: GHRH(1–29) tetrasubstituted analogue; no albumin-binding DAC
Storage: Store at −20 °C; once reconstituted, use promptly under sterile lab conditions
