Semax

Semax

$48.00

Semax is a synthetic heptapeptide analogue of ACTH(4–10), engineered with a Pro-Gly-Pro extension to enhance enzymatic stability and biological activity. In research models it modulates neurotrophic pathways (e.g., BDNF) and stress-response signaling, supporting studies in neuroprotection, synaptic plasticity, and cognition.

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SKU: smx-5
Category: ,

Note: Our products are for in vitro research purposes only and are not for human consumption. The statements made within the website have not been evaluated by the USA Food and Drug Administration.

Batch Details: XA5-A2

Semax is a research-grade peptide derived from the adrenocorticotropic hormone fragment ACTH(4–10) with a C-terminal Pro-Gly-Pro extension to improve stability and receptor engagement. It has been studied for its ability to influence neurotrophic factor expression, neurotransmitter dynamics, and oxidative/inflammatory responses relevant to neural function and recovery.

Research Significance
Modulation of neurotrophic signaling (e.g., BDNF/TrkB) associated with synaptic plasticity
Neuroprotection in models of oxidative stress, hypoxia/ischemia, and neuroinflammation
Cognitive endpoints, including learning, memory, attention, and executive function
Regulation of stress-axis and antioxidant pathways implicated in neuronal resilience

Potential Research Applications
Neuroplasticity and cognition paradigms (LTP, memory consolidation, attention)
Models of ischemia/reperfusion injury and oxidative stress
Neuroinflammatory pathway investigations
Behavioral neuroscience studies on stress adaptation and recovery

Specifications
Form: Lyophilized peptide powder
Content: Semax 5 mg per vial
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
Storage: Store at −20 °C; once reconstituted, use promptly under sterile lab conditions

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